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Isaac Li
Associate Professor
Biochemistry and Molecular Biology, Chemistry
Other Titles: Canada Research Chair (Tier 2)Office: FIP 343
Phone: 250.807.8069
Email: isaac.li@ubc.ca
Graduate student supervisor
Research Summary
Single-molecule biophysics; programmable molecular devices and biosensors; cancer and immune cell biology; cell mechanics and mechanobiology.
Courses & Teaching
Nucleic Acid, Cellular and Molecular Biophysics, Instrumentation, Physical Chemistry
Websites
Single Molecule Mechano-Biology Lab
Degrees
Postdoc, University of Illinois Urbana-Champaign, Center for the Physics of Living Cells (Biophysics)
PhD, University of Toronto (Chemistry)
MASc, University of Toronto (Biomedical Engineering)
BASc, University of Toronto (Engineering Science)
Research Interests & Projects
We study biophysics at the single-molecule and single-cell levels. We are particularly interested in developing tools to understand how cells physically interact with each other and environment. The long-term goal of my research program is to gain mechanistic understandings of mechanobiology processes in disease pathology and develop novel biomedical and biophysical methods for disease diagnosis and treatment. Our current research is focused on the following areas:
- Mechanobiology at the single-molecule level
- DNA-based smart biosensors, molecular machines and biomaterials
- Techniques to manipulate individual molecules and cells
- Disease screening by extracellular vesicles
Please visit the group’s website for more details.
FUNDING
NSERC Discovery, New Frontiers Research Fund (NFRF), Canada Foundation for Innovation (CFI), Emience Fund, Mitacs, UBC, and BC Knowledge Development Fund (BCKDF)
Selected Publications & Presentations
Selected Grants & Awards
Michael Smith Foundation for Health Research Scholar Award
2020 Curricular Innovation Award
Professional Services/Affiliations/Committees
Coordinator for Honours Thesis and Directed Studies in the Department of Chemistry